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Crypto x Agents

The best tools for AI agents to interact with crypto
trade, swap, read on-chain data, manage wallets
and operate autonomously in DeFi.

Agent Frameworks

Full frameworks purpose-built for AI agents that operate on-chain.

Best in Class

GOAT

Great Onchain Agent Toolkit. 200+ onchain tools across 11+ chains, plug into any LLM — wallets, DeFi, NFTs, payments. Sponsored by Crossmint.

Free / Open Source

Both

Most Popular

elizaOS

Multi-agent framework with crypto plugins for EVM, Solana, and social trading. Formerly ai16z; v2 is its most capable agent runtime yet.

Free / Open Source

Both

Enterprise Ready

Coinbase AgentKit

Official Coinbase toolkit for building crypto agents. Wallet creation, trading, staking, and DeFi actions via CDP.

Free

Cloud

Wallets & Transactions

Give your agent a wallet, sign transactions, and interact with smart contracts programmatically.

Best in Class

Crossmint

Wallet-as-a-service with agent-friendly APIs. Create wallets, mint NFTs, handle payments — no private key management.

Freemium

Cloud

Most Secure

Safe (Gnosis)

Smart contract wallets with multi-sig and programmable transaction guards. Ideal for agents that need spending limits.

Free / Open Source

Both

Developer Pick

Viem

Modern TypeScript library for EVM interaction. Send transactions, read contracts, encode calldata — fast, type-safe, minimal.

Free / Open Source

Both

Market Data

Real-time and historical price data, token metadata, and market intelligence for agent decision-making.

Best Free Tier

CoinGecko API

Comprehensive market data — prices, volumes, market caps, trending tokens. Generous free tier, no API key needed for basics.

Freemium

Cloud

Best for DEX

DexScreener

Real-time DEX pair data across all major chains. New pairs, price charts, liquidity, volume — free API with no key.

Free

Cloud

Best EVM Analytics

Codex (Defined)

Real-time token prices, charts, and pair analytics across all major chains via GraphQL. Powers Defined.fi; serves 500M+ API calls/month. New-pair detection built in.

Freemium

Cloud

Trading Frameworks

Execute trades, manage positions, and build strategies across CEXs and DEXs.

Best in Class

CCXT

Unified API for 100+ crypto exchanges. One interface for Binance, Coinbase, Kraken, Bybit — spot, futures, and margin.

Free / Open Source

Both

Best Bot Framework

Freqtrade

Open-source Python trading bot. Backtesting, strategy optimization, live trading. Easily extended with AI/ML signals.

Free / Open Source

Local

Best DEX Aggregator

CowSwap

Intent-based swap protocol with batch auctions. Solvers compete for best execution — MEV protection by design. Python SDK for programmatic orders.

Free

Cloud

MEV Tools

Protect your agent from sandwich attacks — or extract value from arbitrage and liquidation opportunities.

Best Protection

Flashbots Protect

Free private RPC endpoint. Transactions skip the public mempool, blocking sandwich and frontrun attacks. Failed txns cost zero gas. Up to 90% MEV refunds.

Free

Cloud

Most Configurable

MEV Blocker

RPC with 5 endpoint variants — /fast, /noreverts, /fullprivacy, /maxbackruns. Orderflow auction rebates 90% of MEV back to users.

Free

Cloud

For Searchers

Flashbots MEV-Share

Submit backrun bundles against the MEV-Share event stream. Arbitrage and liquidation execution — sandwich attacks architecturally blocked.

Free

Cloud

Cross-Chain Bridging

Move assets between chains programmatically — bridge aggregation so your agent doesn't have to solve routing.

Best in Class

LI.FI

Bridge and DEX aggregator across 60+ chains via 18+ bridges. Single API call finds optimal any-to-any route. TypeScript SDK included.

Freemium

Cloud

Essential Companion

Tenderly

Simulate any transaction before sending. Decoded traces, exact gas, balance changes. Web3 Actions for serverless on-chain event triggers.

Freemium

Cloud

Best Gas Prediction

Blocknative

ML-based gas prediction from real-time mempool data — predicts the next block, not last block. Mempool explorer for pending transaction visibility.

Freemium

Cloud

On-Chain Analytics

Query blockchain data, index events, and build intelligence from on-chain activity.

Best in Class

Flipside

SQL-based blockchain analytics across 20+ chains. Unlimited queries and dashboards on the free tier. 500 API query seconds included.

Free

Cloud

Best for Indexing

The Graph

Decentralized indexing protocol. Query smart contract events and state via GraphQL subgraphs. Essential for DeFi agents.

Freemium

Cloud

Best RPC Provider

Alchemy

Enterprise-grade RPC nodes, enhanced APIs, webhooks, and NFT tooling. The backbone for most production crypto agents.

Freemium

Cloud

Agent Payments

Let your agent actually pay — stablecoin rails and payment protocols built for autonomous, machine-to-machine commerce.

Best in Class

x402

Open HTTP-402 standard for instant stablecoin payments over the web. USDC settlement on Base, Polygon, and more. Incubated under the Linux Foundation; free CDP facilitator tier.

Free / Open Source

Both

Cross-Ecosystem

Google AP2

Agent Payments Protocol — 60+ partners (Mastercard, PayPal, Amex, Coinbase). Cryptographic mandates prove user intent; the A2A-x402 extension adds crypto rails.

Free / Open Source

Both

Turnkey Stack

Skyfire

Identity + payments for agents: fund a wallet, set spending caps, and verify agents with KYA (Know Your Agent). Tokenized-card and stablecoin support.

Freemium

Cloud